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The game is over, as the referee blows his whistle.
Aritz Aduriz gives away a free kick for an unfair challenge on Patrice Evra. Patrice Evra restarts play with the free kick.
The referee shows Aritz Aduriz a yellow card for unsporting behaviour.
John O'Shea is brought on as a substitute for Rafael Da Silva.
Roberto Soldado is penalised for handball and concedes a free kick. Edwin Van der Sar restarts play with the free kick.
Inswinging corner taken by Manuel Fernandes, Rio Ferdinand makes a clearance.
Hernandez Pablo takes a shot. Comfortable save by Edwin Van der Sar.
The ball is swung over by Jeremy Mathieu, clearance by Rio Ferdinand.
Federico Macheda challenges Sanchez Cesar unfairly and gives away a free kick. Free kick taken by Sanchez Cesar.
Nemanja Vidic fouled by Aritz Aduriz, the ref awards a free kick. Edwin Van der Sar restarts play with the free kick.
Mehmet Topal on for David Albelda.
Javier Hernandez gets on the score sheet with a goal from the edge of the penalty area to the bottom right corner of the goal. Valencia 0-1 Man Utd.The assist for the goal came from Federico Macheda.
Federico Macheda joins the action as a substitute, replacing Dimitar Berbatov.
Luis Nani crosses the ball, Shot from inside the six-yard box by Javier Hernandez strikes the post.
Free kick awarded for an unfair challenge on Nemanja Vidic by Roberto Soldado. Edwin Van der Sar takes the free kick.
Javier Hernandez sends in a cross, Sanchez Cesar makes a save.
Roberto Soldado gives away a free kick for an unfair challenge on Luis Nani. Rafael Da Silva takes the direct free kick.
The ball is crossed by Juan Mata, clearance by Rio Ferdinand.
Jeremy Mathieu delivers the ball.
Aritz Aduriz delivers the ball.
The ball is sent over by Hernandez Pablo, Rafael Da Silva makes a clearance.
Inswinging corner taken right-footed by Manuel Fernandes.
Javier Hernandez replaces Oliveira Anderson.
Manuel Fernandes takes a shot. Save by Edwin Van der Sar.
Manuel Fernandes takes a shot. Edwin Van der Sar makes a save.
Luis Nani fouled by Jeremy Mathieu, the ref awards a free kick. Free kick crossed left-footed by Oliveira Anderson.
Manuel Fernandes joins the action as a substitute, replacing Facundo Costa.
The ball is sent over by Luis Miguel, Headed effort on goal by Roberto Soldado from just inside the box goes harmlessly over the goal.
Unfair challenge on Nemanja Vidic by David Navarro results in a free kick. Edwin Van der Sar restarts play with the free kick.
Corner taken left-footed by Facundo Costa, clearance by Rio Ferdinand.
The ball is delivered by Jeremy Mathieu, Rio Ferdinand manages to make a clearance.
Patrice Evra takes a shot. David Navarro gets a block in.
Roberto Soldado takes a shot. Blocked by Michael Carrick.
Luis Nani takes a shot. David Navarro gets a block in.
Inswinging corner taken by Oliveira Anderson, Sanchez Cesar makes a save.
Free kick awarded for a foul by Jeremy Mathieu on Luis Nani. Rafael Da Silva takes the direct free kick.
Facundo Costa delivers the ball, clearance by Nemanja Vidic.
Luis Nani produces a cross, Sanchez Cesar makes a comfortable save.
Roberto Soldado produces a right-footed shot from close range which goes wide of the left-hand upright.
Hernandez Pablo crosses the ball, clearance made by Rafael Da Silva. Corner taken left-footed by Facundo Costa from the left by-line, clearance made by Darren Fletcher.
Aritz Aduriz joins the action as a substitute, replacing Alejandro Dominguez.
Effort from just outside the box by Michael Carrick goes over the bar.
Inswinging corner taken right-footed by Luis Nani, free kick awarded for an unfair challenge on Sanchez Cesar by Nemanja Vidic. Free kick taken by Sanchez Cesar.
Shot by Dimitar Berbatov. Save made by Sanchez Cesar.
Free kick awarded for an unfair challenge on Roberto Soldado by Rio Ferdinand. Facundo Costa takes the direct free kick.
Short corner taken by Oliveira Anderson, The ball is sent over by Luis Nani, save made by Sanchez Cesar.
Hedwiges Maduro fouled by Luis Nani, the ref awards a free kick. Free kick taken by Sanchez Cesar.
The ball is swung over by Roberto Soldado, clearance by Rafael Da Silva.
Hernandez Pablo has an effort at goal from just outside the area which goes wide of the left-hand post.
Dimitar Berbatov produces a cross, blocked by Jeremy Mathieu.
The game restarts for the second half.
The match has reached half-time.
Michael Carrick fouled by Juan Mata, the ref awards a free kick. Direct free kick taken by Edwin Van der Sar.
Juan Mata delivers the ball, Luis Nani makes a clearance.
Juan Mata decides to take the corner short.
Alejandro Dominguez takes a shot. Blocked by Nemanja Vidic.
The ball is swung over by Luis Miguel, Nemanja Vidic manages to make a clearance.
Centre by Jeremy Mathieu, Nemanja Vidic manages to make a clearance.
Foul by Dimitar Berbatov on David Navarro, free kick awarded. Sanchez Cesar takes the free kick.
Juan Mata crosses the ball, Luis Nani manages to make a clearance.
Juan Mata decides to take a short corner.
David Albelda gives away a free kick for an unfair challenge on Michael Carrick. Free kick crossed by Luis Nani, clearance by Roberto Soldado.
Hernandez Pablo sends in a cross.
Hernandez Pablo gives away a free kick for an unfair challenge on Rio Ferdinand. Direct free kick taken by Rio Ferdinand.
Hernandez Pablo sends in a cross, Rafael Da Silva makes a clearance.
Free kick awarded for an unfair challenge on Patrice Evra by Luis Miguel. Michael Carrick takes the direct free kick.
Foul by Hedwiges Maduro on Dimitar Berbatov, free kick awarded. Darren Fletcher takes the direct free kick.
Centre by Jeremy Mathieu.
Free kick awarded for an unfair challenge on Jeremy Mathieu by Rafael Da Silva. Free kick taken by Sanchez Cesar.
The ball is crossed by Luis Nani, Oliveira Anderson has an effort at goal from close in which goes wide right of the target.
The ball is crossed by Facundo Costa, Roberto Soldado produces a header from inside the six-yard box that clears the bar.
Shot from just outside the area by Hernandez Pablo goes over the bar.
A cross is delivered by Hernandez Pablo.
Foul by Darren Fletcher on Hernandez Pablo, free kick awarded. Free kick crossed left-footed by Facundo Costa.
Foul by David Navarro on Oliveira Anderson, free kick awarded. Michael Carrick takes the free kick.
Jeremy Mathieu fouled by Luis Nani, the ref awards a free kick. Sanchez Cesar restarts play with the free kick.
Free kick awarded for an unfair challenge on Darren Fletcher by Facundo Costa. Darren Fletcher takes the direct free kick.
Dimitar Berbatov has an effort at goal from outside the area missing to the wide right of the target.
The ball is crossed by Roberto Soldado, save by Edwin Van der Sar.
The game kicks-off.
Manchester United headed to Valencia without Wayne Rooney but nursing a deep determination to get their season back on track.
It could be argued Rooney's struggle for form has been a contributing factor to a stop-start opening that has seen United register four draws from seven matches in all competitions.
Yet that only tells part of the story, which is why Rooney's absence from the team flight to Spain through an ankle injury should have minimal effect.
Of far more importance is defensive solidity, which has been strangely absent for United so far but which they will undoubtedly require on Wednesday if they are to avoid defeat against a side that has shrugged off the summer departures of David Villa and David Silva to become the surprise early-season pace-setters in the Primera Division.
"It is going to be a difficult match," said midfielder Darren Fletcher.
"People might say it is not the same Valencia because they have lost Villa and Silva. But as we have seen at Manchester United, when you lose good players others step up to the mark and take on more responsibility. They have had a fantastic start."
United, and in particular Rooney, cannot say the same. Dimitar Berbatov has been the Red Devils' stand-out offensive player so far this season and Michael Owen has scored three times in a week, so there was an argument that Rooney did not deserve to be selected this week anyway.
His ankle injury, which is set to keep him out for around three weeks, has provided a reason for Ferguson to leave him at home, which will allow the 24-year-old a chance to get his mind right following damaging allegations about his private life.
Confirming his absence at this early stage, matchday two should be relatively free of diversions.
None of this should deviate Rooney's team-mates - also shorn of the injured Antonio Valencia and Ryan Giggs - from their task of avoiding defeat in one of Europe's most impressive stadiums, the Mestalla.
"We have picked up experience of playing in Europe and we have confidence," said Fletcher.
"We know how to cope with the travel and the different styles of play.
"Against Spanish sides, keeping the ball is key. If you give the ball away cheaply, you might not see it for a few minutes and they will punish you."
Rio Ferdinand is set to partner Nemanja Vidic in central defence for the first time this season.
Ferdinand's two appearances since recovering from the knee injury that wrecked his World Cup have both been when Vidic has been rested.
But after watching his side concede nine goals in their past five Premier League games, Sir Alex Ferguson could not have chosen a better time to get his first-choice pairing back together.
With Paul Scholes set to be rested, Michael Carrick could make his first-team return.
The midfielder has not started a game for United since the Community Shield and, although he did join up with the England squad for their opening Euro 2012 qualifiers, he was then sent for an injection to try to ease the discomfort from a niggling Achilles problem.
Hernandez wins it
Manchester United new-boy Javier Hernandez chose the perfect time to net his first competitive goal for the Red Devils as his 85th-minute winner proved too much for Valencia and gave United a 1-0 win.
Although United rarely looked like breaking their sequence of three successive goalless draws in Spain, Sir Alex Ferguson will not care too much about that.
The mere fact Hernandez's goal, drilled expertly into the far corner after fellow substitute Federico Macheda had cut a cross back from the right, proved United with only their second victory in 19 attempts against Spanish opposition in Spanish soil tells you just how hard it is.
Instead of having ground to make up in the battle to reach the knock-out phase, United can now look forward to back-to-back clashes with Group C makeweights Bursaspor knowing six points will virtually secure their place in the last 16 of this season's Champions League.
Having called for greater defensive solidity, the return of Rio Ferdinand ensured Ferguson got it and now United will hope to take that form into their Premier League challenge as well following recent hiccups.
Ferguson only needed to look at the record books to understand how hard it would be to win.
On 18 trips to Spain to face Spanish opposition, the solitary victory came against Deportivo La Coruna in 2002.
United's last three visits had ended goalless, which would probably have been an acceptable outcome from what on paper at least is their hardest Group C fixture, even taking into account that surprising stalemate with Rangers at Old Trafford a fortnight ago.
It seemed Valencia would not be too displeased either given the cautious manner with which they attempted to find a way through a side for whom Dimitar Berbatov was expecting forward support from Anderson.
Berbatov last started a match in this competition in Moscow 11 months ago. It was 12 months prior to that since his last goal.
He came close to ending the drought when he cut inside from the left touchline where he spent so much time and curled a shot just wide.
That represented the sum total of United's threat to the Valencia goal, although, with Rio Ferdinand back to reinforce their own rearguard, they looked far more secure than in recent weeks and restricted their hosts to general pressure rather than clear-cut opportunities.
Their best came through a rare mistake from Edwin van der Sar, who completely failed to cut out Alejandro Dominguez's right-wing cross.
Roberto Soldado seemed to be waiting more in hope than expectation of getting his head on the ball and it showed as he reacted to what was actually a clear sight of goal far too slowly and turned it over.
Pablo Hernandez was Valencia's danger-man, though, fizzing a couple of crosses into dangerous areas before the break, then firing wide of the far-post immediately after it after he had cut in from his right-wing station.
Ferguson needed his side to make better use of their possession.
Park Ji-sung was lucky to survive into the second period after receiving a rocket from his manager for giving the ball away rather too often.
Berbatov is rarely guilty of that offence and after bursting past David Navarro failed to take his second opportunity of the game when Cesar Sanchez made an important feet-first save, even if the Bulgarian had been trying to score from an acute angle.
With a combined debt of #1.136billion - building work on a new stadium that started in 2007 has stopped completely and David Villa and David Silva were sold to Barcelona and Manchester City in the summer to ease Valencia's financial situation - the winning prize money would come in handy.
Neither side looked like getting one, or deserved to given the paucity of chances.
The introduction of Manuel Fernandes did trigger an improvement from Valencia.
Van der Sar needed to push away the midfielder's long-range effort before Soldado came close to turning home Aritz Aduriz's cross with a desperate attempt at a diving header.
It looked for all the world like ending in a stalemate. Hernandez had other ideas.
"Barclays Premier League Predictions - 2012/13"