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The ball is crossed by Luke Shaw.
The referee signals the end of the game.
Free kick awarded for an unfair challenge on Harrison Reed by Samir Nasri.
Clearance made by Calum Chambers.
Aleksandar Kolarov sends in a cross.
Clearance by Vincent Kompany.
Gaston Ramirez crosses the ball in from the free kick.
(Southampton) makes a substitution, with Harrison Reed coming on for Steven Davis.
Calum Chambers fouled by Samir Nasri, the ref awards a free kick.
Free kick taken by Paulo Gazzaniga.
The offside flag is raised against Sergio Aguero.
Clearance made by Paulo Gazzaniga.
Header at goal by Sergio Aguero misses left of the target.
The ball is crossed by Francisco Javi Garcia.
Gaston Ramirez on for Adam Lallana.
The official flags Rickie Lambert offside.
Jay Rodriguez is flagged offside by the assistant referee.
Clearance by Dejan Lovren.
Jack Cork challenges Pablo Zabaleta unfairly and gives away a free kick.
The referee blows for offside.
Edin Dzeko comes on in place of Yaya Toure.
The official flags Sergio Aguero offside.
Foul by Samir Nasri on Steven Davis, free kick awarded.
Adam Lallana is caught offside.
Rickie Lambert is brought on as a substitute for Pablo Osvaldo.
Clearance made by Vincent Kompany.
Aleksandar Kolarov takes a fantastic shot and missed to the left of the goal.
Free kick crossed by James Ward-Prowse.
Foul by Aleksandar Kolarov on Adam Lallana, free kick awarded.
Foul by Luis Fernandinho on James Ward-Prowse, free kick awarded.
Francisco Javi Garcia makes a clearance.
Corner from the right by-line taken by Samir Nasri.
Clearance made by Jack Cork.
Pablo Zabaleta manages to make a clearance.
Sergio Aguero takes the chance to get an effort at goal and missed to the right of the net.
The ball is swung over by Calum Chambers.
Corner taken by James Ward-Prowse.
Dejan Lovren restarts play with the free kick.
Unfair challenge on Dejan Lovren by Sergio Aguero results in a free kick.
Gonzalez Jesus Navas is brought on as a substitute for Alvaro Negredo.
James Milner leaves the field to be replaced by Francisco Javi Garcia.
Aleksandar Kolarov produces a cross.
Pablo Zabaleta makes a clearance.
Steven Davis has an effort at goal. Costel Pantilimon safely holds on.
The ball is swung over by Adam Lallana.
Pablo Osvaldo takes a shot and missed to the right of the net.
Luke Shaw delivers the ball.
Clearance made by Dejan Lovren.
Pablo Osvaldo takes a shot and cleared the crossbar.
Clearance made by Martin Demichelis.
James Milner fouled by Luke Shaw, the ref awards a free kick.
Jose Fonte manages to make a clearance.
Sergio Aguero has an effort at goal. A parry by Paulo Gazzaniga prevents the goal.
The ball is swung over by Samir Nasri.
Clearance made by Jose Fonte.
Free kick taken by Costel Pantilimon.
The second half begins.
The half-time whistle blows.
Free kick taken by Aleksandar Kolarov.
Unfair challenge on Aleksandar Kolarov by James Ward-Prowse results in a free kick.
Vincent Kompany manages to make a clearance.
Pablo Osvaldo scores with their right foot. Southampton 1-1 Man City.Assist by Steven Davis.
Clearance by Paulo Gazzaniga.
Free kick awarded for an unfair challenge on Aleksandar Kolarov by Calum Chambers.
James Ward-Prowse takes the chance to get an effort at goal. Costel Pantilimon safely holds on.
Free kick taken by Luke Shaw.
James Milner concedes a free kick for a foul on Luke Shaw.
Header by Calum Chambers misses to the right of the target.
Shot by Sergio Aguero. Paulo Gazzaniga blocks the ball.
Adam Lallana takes the chance to get an effort at goal and missed to the right of the net.
The ball is crossed by Dejan Lovren.
The ball is crossed by Calum Chambers.
Shot by Sergio Aguero went harmlessly over the bar.
The ball is swung over by Luke Shaw.
Jay Rodriguez has an effort at goal. Pablo Zabaleta gets a block in.
Adam Lallana has an effort at goal. Blocked by Pablo Zabaleta.
Alvaro Negredo produces a cross.
The ball is sent over by Calum Chambers.
Corner from the left by-line taken by James Ward-Prowse.
Unfair challenge on James Ward-Prowse by Yaya Toure results in a free kick.
Dejan Lovren makes a clearance.
Jose Fonte restarts play with the free kick.
Jose Fonte fouled by Alvaro Negredo, the ref awards a free kick.
Clearance made by Sergio Aguero.
Calum Chambers makes a clearance.
Free kick crossed by Samir Nasri.
Dejan Lovren concedes a free kick for a foul on Alvaro Negredo.
Vincent Kompany makes a clearance.
Corner from the left by-line taken by Samir Nasri.
Samir Nasri delivers the ball.
The referee penalises Adam Lallana for handball.
Sergio Aguero slots the ball left footed into the goal. Southampton 0-1 Man City.Aleksandar Kolarov provided the assist for the goal.
Clearance by Jose Fonte.
Clearance by James Ward-Prowse.
Luis Fernandinho has an effort at goal and missed to the left of the goal.
Steven Davis takes the chance to get an effort at goal and missed to the left of the net.
The ball is sent over by Luke Shaw.
Dejan Lovren manages to make a clearance.
The ref blows the whistle to start the match.
Nothing's changed for Pochettino
A run of three successive defeats and an ever-mounting injury list is hardly the best preparation for taking on Manchester City, yet Mauricio Pochettino is confident Southampton can enjoy an upturn in fortunes against the title hopefuls.
Saints began the season as the toast of English football, with their blend of home-grown talent and big-money signings impressing in an attractive, high-tempo style.
Not only that, they were also getting results and could have gone top of the Barclays Premier League with victory at Arsenal two weeks ago.
However, Saints have slumped to eighth after a run of three successive defeats and now face the unenviable task of attempting to thwart in-form City.
That challenge has been made all the more difficult by injuries picked up by Victor Wanyama and Nathaniel Clyne in the midweek defeat to Aston Villa, swelling the possible first-team absentees for the game to eight.
"I believe that every game is a test, not just against Manchester City," the Argentinian said ahead of Saturday's match. "Every single game is a very large test for us.
"It is clear that we picked up some injuries against Aston Villa that we did not have in the past, but nothing has changed within this team.
"This team still believes, it still believes in how we play, and what a great chance for us to go and invert this negative run we are on in front of our fans in a great stadium. This is a very good chance for us to change our fortunes right now."
Such positivity will surprise many onlookers given some of the names on Southampton's injury list.
Wanyama and Clyne are joined on the sidelines by Morgan Schneiderlin, Guly do Prado and Danny Fox, while Jose Fonte, so impressive at centre-back alongside Dejan Lovren, is a doubt.
Third-choice goalkeeper Paulo Gazzaniga will again deputise in goal as Artur Boruc fractured his hand last week and back-up Kelvin Davis is struggling with a side injury.
It makes a result like February's 3-1 defeat of City - the first victory of Pochettino's reign - look a tough ask, yet he is confident in the strength in depth at his disposal.
The Saints boss has already named 12 players from the youth system in the matchday squad this season and believes harnessing young talent will be key moving forwards.
"I am confident that we can overcome this bad run that we are on," Pochettino said. "That is what we are working for.
"The project in Southampton is to mix very young players with a lot more experienced players.
"This is a big test for us right now and it also gives us a good chance to bring some of the younger players, such as Harrison Reed, Sam Gallagher, Cody Cropper, Matt Targett, Will Britt.
"It is a very good experience for them to be in the mix with more veteran players in the senior side. It is a very good chance for us to execute that plan to bring younger players into the side."
Most of those young players will only make up the numbers for now, with Adam Lallana, James Ward-Prowse, Luke Shaw and Calum Chambers the only academy graduates likely to start against City.
It is a match that not only gives Saints the chance to get back on track, but for former Espanyol manager Pochettino to get one over on old foe Manuel Pellegrini, a man he knows well from his time in Spain.
"I have many memories of having faced Manuel Pellegrini in La Liga, when he was Villarreal, Malaga and Real Madrid," he said.
"I even knew him when I was with Under-18s in Argentina. He was managing the Chile Under-20s some 25 years ago.
"I have great respect for him. I wouldn't say that we were friends, but we have a great working relationship and he is someone I admire. We have a very good professional relationship."
Pellegrini insists the Barclays Premier League results in midweek have not changed which sides are, and are not, in the title race.
While City, leaders Arsenal, Chelsea, Liverpool and Tottenham all won on Wednesday, champions Manchester United suffered a 1-0 home defeat to Everton.
The Red Devils are now ninth in the table, 12 points behind the Gunners, with all teams in the division having played 14 games.
It does not look promising for United's hopes of defending their crown, but Pellegrini thinks the title battle remains "exactly the same".
Asked about Wednesday's results and if he thought United were now out of the race, Pellegrini - whose side triumphed 3-2 at West Brom - said: "It was an important game for us, winning the three points away.
"I think the fight for the Premier League is exactly the same. There are eight or nine teams that are very close in points.
"For us, it is very important to continue winning.
"But we have five more games to complete the first half (of the season) and then we have all the second half."
Pellegrini was speaking at a press conference to preview Saturday's top-flight visit to Southampton.
Prior to the West Brom result, City - who are third, six points behind Arsenal - had won only one of six Premier League away games in 2013-14, losing four of them.
Beating Albion was certainly a boost ahead of the Saints trip, although Pellegrini has stressed that even prior to the match at The Hawthorns, there had been no issues with his players' confidence regarding their ability to secure victories on the road.
"I think that before the West Brom game, we didn't have any problems psychologically about winning away," the Chilean said.
"Maybe you think there is a different reason, but I was absolutely sure it was just about the points - not tactical problems, and I am also sure the squad had the confidence.
"We were sure we were going to start winning. So then that (West Brom) was first, and now we must repeat it tomorrow."
Eighth-placed Southampton go into the encounter off the back of three straight defeats - a notable run of results in the tenure of Pochettino as their manager.
The 41-year-old Argentinian, who previously coached in Spain at the same time as Pellegrini, has done an impressive job overall since succeeding Nigel Adkins in January.
Southampton beat City 3-1 at St Mary's shortly after that appointment and Wednesday's 3-2 reverse against Aston Villa was the Saints' first home defeat this term.
Pellegrini does not know how Pochettino's men will react on Saturday, but sees it as a dangerous thing that they are hurting from a succession of losses.
The 60-year-old said of his fellow south American: "I know him very well. He is a very good manager and I think he is doing a great job with Southampton - he also did in Spain.
"I am sure we are playing against a strong team.
"I think playing against a team as good as Southampton, when they have lost the last three games, will be more difficult for us.
"I don't know what the reaction of Southampton will be. They are a young team, and they have a young manager.
"But he knows perfectly how he must manage this situation."
Pellegrini is optimistic City captain Vincent Kompany will be fine to keep his place in the team for Saturday's match.
The Belgium defender, who has been sidelined by a thigh problem, made his first appearance since October 5 on Wednesday when he played for the whole of the West Brom contest.
Regarding Kompany, Pellegrini said: "We will see if he can play two matches in less than three days. But he is okay.
"It is not an easy decision. But I think he finished the last game without any problem.
"We will wait to see that he has made the perfect recovery and I will decide. But I don't think it is a great risk for him to play another game."
Striker Stevan Jovetic, defender Matija Nastasic and playmaker David Silva will all miss out due to their calf injuries, but Pellegrini has indicated the latter of the trio could be involved in Tuesday's Champions League match at Bayern Munich.
The manager once again would not confirm whether Costel Pantilimon would be retained in goal or Joe Hart brought back in his place.
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