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Ibrahim Afellay is brought on as a substitute for Andres Iniesta.
Shot by Rodriguez Pedro from outside the area goes high over the crossbar.
Hernandez Xavi finds the net with a goal from inside the penalty area to the bottom left corner of the goal. Barcelona 5-1 Shakhtar Donetsk.Assist on the goal came from da Silva Dani Alves.
Santos Alex Teixeira challenges Andres Iniesta unfairly and gives away a free kick. Sergio Busquets takes the direct free kick.
The referee blows for offside. Indirect free kick taken by Victor Valdes.
Da Silva Eduardo joins the action as a substitute, replacing Tomas Hubschman.
Lionel Messi is flagged offside by the assistant referee. Indirect free kick taken by Andrei Pyatov.
Effort from inside the six-yard area by da Silva Luiz Adriano hits the post.
Andres Iniesta takes a shot from just inside the penalty box which clears the crossbar.
Henrikh Mkhitaryan challenges Rodriguez Pedro unfairly and gives away a free kick. Sergio Busquets restarts play with the free kick.
Free kick awarded for a foul by Tomas Hubschman on Javier Mascherano. Hernandez Xavi takes the free kick.
Luis Fernandinho receives a caution. Claro Adriano Correia goes off and Scherer Andrade Maxwell comes on. Free kick awarded for an unfair challenge on Gerard Pique by Luis Fernandinho. Free kick taken by Sergio Busquets.
Santos Alex Teixeira on for da Silva Willian. The referee blows for offside against Razvan Rat. Sergio Busquets restarts play with the free kick.
Unfair challenge on Lionel Messi by Luis Fernandinho results in a free kick. Da Silva Dani Alves has a direct shot on goal from the free kick.
Rodriguez Pedro replaces David Villa.
Rodrigues Jadson goes off and Luis Fernandinho comes on.
De Souza Douglas Costa decides to take the corner short.
David Villa is ruled offside. Andrei Pyatov takes the indirect free kick.
Yaroslav Rakitskiy is booked. Yaroslav Rakitskiy gives away a free kick for an unfair challenge on David Villa. Hernandez Xavi restarts play with the free kick.
The assistant referee signals for offside against David Villa. Yaroslav Rakitskiy restarts play with the free kick.
Inswinging corner taken from the right by-line by Hernandez Xavi.
Lionel Messi takes a shot. Save by Andrei Pyatov.
Seydou Keita grabs a goal from deep inside the penalty box to the top left corner of the goal. Barcelona 4-1 Shakhtar Donetsk.The assist for the goal came from Lionel Messi.
Andres Iniesta receives a yellow card for unsporting behaviour. Yaroslav Rakitskiy finds the net with a goal from deep inside the penalty box to the bottom left corner of the goal. Barcelona 3-1 Shakhtar Donetsk.Javier Mascherano challenges Darijo Srna unfairly and gives away a free kick. Assist on the goal came from Darijo Srna.
Corner taken short by da Silva Willian.
Gerard Pique fires in a goal from the edge of the penalty box to the bottom left corner of the goal. Barcelona 3-0 Shakhtar Donetsk.Corner taken right-footed by Hernandez Xavi, the assist for the goal came from Hernandez Xavi.
Mykola Ischenko concedes a free kick for a foul on Seydou Keita. Claro Adriano Correia takes the free kick.
Razvan Rat is given a yellow card. Razvan Rat gives away a free kick for an unfair challenge on da Silva Dani Alves. Hernandez Xavi shoots direct from the free kick, save by Andrei Pyatov.
Free kick awarded for an unfair challenge on Darijo Srna by Andres Iniesta. Free kick taken by Darijo Srna.
Lionel Messi takes a shot. Andrei Pyatov makes a save.
Da Silva Dani Alves crosses the ball.
Henrikh Mkhitaryan gives away a free kick for an unfair challenge on Andres Iniesta. Free kick taken by Andres Iniesta.
The assistant referee signals for offside against da Silva Luiz Adriano. Indirect free kick taken by Victor Valdes.
Centre by de Souza Douglas Costa.
Henrikh Mkhitaryan challenges Claro Adriano Correia unfairly and gives away a free kick. Gerard Pique takes the direct free kick.
Darijo Srna gives away a free kick for an unfair challenge on Claro Adriano Correia. Victor Valdes restarts play with the free kick.
Darijo Srna decides to take a short corner.
The ball is sent over by Darijo Srna, blocked by Claro Adriano Correia.
Da Silva Dani Alves grabs a goal from close range low into the middle of the goal. Barcelona 2-0 Shakhtar Donetsk.Andres Iniesta provided the assist for the goal.
De Souza Douglas Costa gives away a free kick for an unfair challenge on Sergio Busquets. Gerard Pique restarts play with the free kick.
Da Silva Dani Alves gives away a free kick for an unfair challenge on da Silva Willian. Razvan Rat takes the free kick.
Foul by Razvan Rat on David Villa, free kick awarded. Da Silva Dani Alves restarts play with the free kick.
The ball is swung over by da Silva Dani Alves, David Villa takes a shot. Save made by Andrei Pyatov.
David Villa takes a shot. Save by Andrei Pyatov.
De Souza Douglas Costa takes a shot. Victor Valdes makes a save.
Seydou Keita fouled by Henrikh Mkhitaryan, the ref awards a free kick. Claro Adriano Correia takes the direct free kick.
Free kick awarded for a foul by da Silva Dani Alves on da Silva Willian. Razvan Rat restarts play with the free kick.
David Villa has an effort at goal from outside the penalty area missing to the wide left of the goal.
Outswinging corner taken from the right by-line by Hernandez Xavi.
The referee blows for offside. Sergio Busquets restarts play with the free kick.
Rodrigues Jadson fouled by Javier Mascherano, the ref awards a free kick. Andrei Pyatov restarts play with the free kick.
Centre by Claro Adriano Correia, Razvan Rat manages to make a clearance.
De Souza Douglas Costa challenges Sergio Busquets unfairly and gives away a free kick. Sergio Busquets restarts play with the free kick.
The official flags Razvan Rat offside. Da Silva Dani Alves takes the direct free kick.
Andres Iniesta challenges Darijo Srna unfairly and gives away a free kick. Andrei Pyatov takes the direct free kick.
Shot by Lionel Messi. Save by Andrei Pyatov.
Claro Adriano Correia produces a drilled right-footed shot from 20 yards. Blocked by Darijo Srna.
De Souza Douglas Costa challenges Andres Iniesta unfairly and gives away a free kick. Lionel Messi produces a shot on goal direct from the free kick.
Darijo Srna gives away a free kick for an unfair challenge on Andres Iniesta. Claro Adriano Correia takes the direct free kick.
Unfair challenge on Henrikh Mkhitaryan by Seydou Keita results in a free kick. Tomas Hubschman restarts play with the free kick.
Sergio Busquets produces a right-footed shot from inside the six-yard box that clears the bar.
Short corner taken by Hernandez Xavi.
Lionel Messi takes a shot. Blocked by Darijo Srna.
Shot from a long way out by da Silva Willian goes wide of the left-hand post.
Da Silva Luiz Adriano has an effort from just inside the box that misses to the left of the goal.
Darijo Srna fouled by Seydou Keita, the ref awards a free kick. Direct free kick taken by Andrei Pyatov.
Free kick awarded for a foul by Lionel Messi on Yaroslav Rakitskiy. Yaroslav Rakitskiy restarts play with the free kick.
Darijo Srna crosses the ball, da Silva Dani Alves makes a clearance.
The assistant referee signals for offside against da Silva Willian. Victor Valdes takes the indirect free kick.
The ball is sent over by da Silva Willian, save by Victor Valdes.
Tomas Hubschman challenges Lionel Messi unfairly and gives away a free kick. Andres Iniesta takes the direct free kick.
Effort from outside the area by Henrikh Mkhitaryan goes wide right of the goal.
Andres Iniesta finds the net with a goal from close in to the bottom left corner of the goal. Barcelona 1-0 Shakhtar Donetsk.
Barcelona head into their Champions League clash against Shakhtar Donetsk in buoyant mood, although striker David Villa admits to concern over his recent lack of goals at club level.
Barca now boast an eight-point advantage over Real Madrid at the Primera Division summit with only eight games remaining after Pep Guardiola's men took full advantage of Madrid's shock home defeat to Sporting Gijon by beating third-placed Villarreal 1-0.
Gerard Pique was Barca's match-winner in that game as Villa again failed to end his goalscoring drought for the Catalan giants.
Although he recently became Spain's record goalscorer with a brace against the Czech Republic, Villa has not found the back of the net in his last six outings for Barca - having previously struck in four successive matches and notched 21 goals for the club since his big-money summer move from Valencia.
Villa said: "Whenever you don't score you get a little worried, but what I have to do is work hard in training and in games and be calm. You have hardly any time to decide what to do (in front of goal), and sometimes you decide well, and other times you make a bad choice and don't score. A goal will arrive and if I don't score a team-mate will."
Despite Villa's barren spell, Barca have barely broken stride, winning seven and drawing the other of their last eight games to continue their bid for a second treble in three seasons.
It is looking especially good in La Liga, but Villa said: "To have an eight-point lead with eight games left is a considerable difference, but we must not fall into the error of thinking we are champions. Right now only we can lose the league."
Barca are also in the final of the Copa del Rey, where they face Real Madrid later this month, while they will hope to further boost their hopes of Champions League success when they host Shakhtar in the first leg of their quarter-final clash.
Villa, who has never reached the semi-finals before, said: "When you come into a game after losing or drawing, everyone knows you have to put it behind you and concentrate on the next match, but the same thing holds true if you've just won.
"We are playing at home, in front of our fans, and we need a good result so as not to suffer too much in the return leg."
Shakhtar are underdogs against the 2006 and 2009 European champions, but the Ukrainian outfit know what it is like to win at the Nou Camp.
They won 3-2 in the Catalan city in 2008 - albeit against a much-changed home side - while Shakhtar also pushed Barca all the way in the final of the 2009 UEFA Super Cup before going down to a Pedro Rodriguez goal in the 115th minute.
Shakhtar captain Darijo Srna heaped praise on Barca, but warned Guardiola's men that his side have nothing to lose heading into the game.
He said in www.sport.es: "We are facing an immense team, they are the best team in the world and in my view I think they are the best football team in history.
"We've already achieved our goal of being among the best eight teams in Europe. It's a great success, and now we feel no pressure, we're going to go out on the pitch and play football. It will be tough, but I can promise our fans that we are going to give it everything. We're going to try and get a good result there because we know that it's very difficult for any team to beat us at the Donbass Arena."
Srna was on the mark as Shakhtar warmed up for the game with a 3-1 win at Illychivets Mariupol on Friday, leaving Mircea Lucescu's side 12 points clear at the top of the table.
Brazilian midfielder Fernandinho made his return in that match after seven months out injured.
Five-star Barca destroy Donetsk
Barcelona all but secured their spot in the Champions League semi-finals and a probable showdown with arch rivals Real Madrid after building a huge 5-1 first-leg lead over Shakhtar Donetsk.
Following on from Madrid's 4-0 thumping of Tottenham, Barca appear to have done all the hard work in their home quarter-final tie after another memorable European night at the Nou Camp.
Andres Iniesta, Dani Alves, Gerard Pique, Seydou Keita and Xavi were on the mark for the Catalan giants, while Shakhtar's sole reply came from Yaroslav Rakitskiy when they were already 3-0 down.
Barca coach Pep Guardiola had admitted he had a bad feeling about this match, but his fears will have been eased after seeing his take the lead after just 99 seconds through new father Iniesta.
The Spanish World Cup winner, whose wife gave birth on Sunday, slotted a low shot past visiting goalkeeper Andrei Pyatov at his near post after picking up a loose ball in the area.
However, 10 minutes after that goal, Barca survived two huge scares in quick succession as they rode their luck at the back.
The first opportunity saw Luiz Adriano beat stand-in Barca centre-back Sergio Busquets to a through-ball but then fire wide with only Victor Valdes to beat.
Then, just moments later, a bad attempted back-pass from Dani Alves forced Valdes to race out of his goal and, although he beat Luiz Adriano to the ball, his clearance went straight to Willian whose first-time shot from 30 yards out dropped just wide of an open net.
Barca survived though and almost profited from some slack defending themselves in the 19th minute, as Messi robbed Mykola Ischenko of possession on the edge of the Shakhtar area but his attempted chip over Pyatov was saved.
Barca, who also went close through a Messi free-kick and a David Villa shot, were celebrating a second goal soon enough though as Alves netted after latching onto an inch-perfect pass by Iniesta.
Iniesta's lofted ball in towards the penalty spot might have been collected by Pyatov but, as the goalkeeper waited for the ball, Alves nipped in to steal possession before slotting into an empty goal.
That was the score Barca led by at half-time, but the 2006 and 2009 European champions wasted no time in trying to build on that advantage at the start of the second period.
Messi and Xavi both had efforts saved before Guardiola's side made it 3-0 in the 53rd minute through Pique following a training-ground move.
Xavi cut a low corner back towards the edge of the area to meet the run of Pique, who had escaped his marker, and the Spain centre-back's first-time shot took a deflection off Rakitskiy before beating the wrong-footed Pyatov.
At that point Barca looked to be cruising into the semi-finals but Shakhtar gave themselves a glimmer of hope after netting an away goal in the 58th minute, with Rakitskiy making the decisive touch at the right end this time.
Darijo Srna's free-kick into the area was flicked on by Rakitskiy at the near post and Valdes was unable to keep the ball out as it flew into the far side of the goal.
Shakhtar's hope was short-lived however as Barca immediately went down the other end and restored their three-goal lead.
Messi beat his man before rolling a pass across the edge of the area to the unmarked Keita, who slammed an unstoppable shot into the near top corner of the net.
Barca survived another let-off with nine minutes remaining when Luiz Adriano struck the inside of the far post, and if that had gone it in would have made for an interesting second leg.
However, the ball stayed out and Barca all but killed the tie off by notching a fifth goal in the 86th minute when Xavi slotted in Alves' pass.
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