Jordan Spence is expected to go straight into the MK Dons starting line-up against Tranmere.
Spence has re-joined the Dons on loan until the end of the season. The West Ham defender played 12 games for Karl Robinson's side in his first spell at stadiummk earlier this season, the last of which was a goalless home draw with Colchester on New Year's Day.
The versatile 23-year-old, who can play at right-back or centre-back, should partner Antony Kay in the centre of defence on Saturday.
Elsewhere, the Dons have no fresh injury concerns after both Lee Hodson (knee) and Dele Alli (leg) both returned to action in the midweek defeat at Carlisle.
Full-back Liam Ridehalgh could return to give Tranmere boss Ronnie Moore a full complement of options.
The left-back has missed Rovers' last two games with a groin problem so Evan Horwood has filled in, but Moore is confident that if he shows no adverse reaction from Thursday's training session, he will be ready to feature.
Tranmere have been beset by injuries in recent weeks but the treatment room has now cleared with defenders Ian Goodison (thigh) and Danny Holmes (back) hoping to return to the starting line-up.
Midfielder Jason Koumas had started Rovers' previous eight games in a row before dropping to the bench against Rotherham in midweek, so he will hoping for a recall alongside captain James Wallace in the centre of the park.