Arsenal have been drawn against holders Barcelona in the quarter-finals of the Champions League, while Manchester United face Bayern Munich in a repeat of the memorable 1999 Final.
Barcelona beat the Gunners in the Final four years ago when Arsene Wenger's team had Jens Lehmann sent off and outclassed Manchester United in last year's showpiece.
Eleven years ago United produced one of the most memorable comebacks in European football history when they scored two last-gasp goals to edge past the current Bundesliga leaders 2-1.
The German side seemed certain to claim the trophy when they led 1-0 going into injury time only for last-gasp goals by substitutes Teddy Sheringham and Ole Gunnar Solskjaer to hand Sir Alex Ferguson his first Champions League crown.
Elsewhere, there will be an all-French quarter-final after Lyon were paired with Bordeaux while Internazionale, who knocked Chelsea out of the competition on Tuesday, will be expected to see off outsiders CSKA Moscow, who surprisingly beat Sevilla at the last-16 stage.
If United can win through to the semi-finals they will play the winners of the Lyon v Bordeaux clash, while Arsenal will face Inter or CSKA if they can shock Pep Guardiola's team.
The full quarter and semi-final draws are:
Lyon v Bordeaux
Bayern Munich v Manchester United
Arsenal v Barcelona
Internazionale v CSKA Moscow.
Bayern Munich or Manchester United v Lyon or Bordeaux
Internazionale or CSKA Moscow v Arsenal v Barcelona.