Manchester United striker Wayne Rooney is a major doubt for England's friendly with Spain on Wednesday after picking up a back injury in Sunday's 4-0 victory over Tottenham.
Rooney was replaced after 64 minutes of the White Hart Lane clash by Louis Saha and afterwards United boss Sir Alex Ferguson admitted the substitution was a precautionary measure.
"Wayne was injured in a challenge and he limped around for a bit but I had to take him off," said Ferguson.
"I'll assess what he's like in the morning but he may be a doubt for the game on Wednesday."
Meanwhile, Tottenham's Jermaine Jenas has pulled out of the England squad after suffering a recurrence of a recent ankle injury.
The midfielder made a goalscoring return in last weekend's FA Cup victory over Southend before picking up a fresh problem in the midweek Carling Cup defeat against Arsenal.
However, Spurs boss Martin Jol doesn't expect the former Newcastle and Nottingham Forest midfielder to be sidelined for too long.
He said: "In England you have to stay with your runner and pick up people in the final third.
"But we'll turn it around because next week Jermaine Jenas will come back and he's a player who can do that."