Manchester United will struggle to cope without Nemanja Vidic in their Champions League last 16 clash with Internazionale, according to Jose Mourinho.
The Inter coach believes the loss of the Serbia defender to suspension for one game - Tuesday's first-leg meeting at the San Siro - will come as a huge blow to the reigning European champions.
Mourinho has also struck first in the pre-match mind games after suggesting Vidic should be banned for both legs of the tie after being sent off in the Club World Cup Final in December.
"I think Nemanja Vidic should be suspended for both legs, not just this week's game," he wrote in his column for the Daily Telegraph.
"We will certainly try to make things uncomfortable for the United defence without him at the San Siro.
"We have almost the whole squad fit and with the support of our fans and the experience of our players, we can make this very, very tough for United.
"It will not be an open game - we want it to be tight and tactical."
Meanwhile, United have been boosted after both Jonny Evans and John O'Shea travelled with the squad to Italy.
Either Evans or O'Shea were expected to deputise for Vidic, but the former limped out of Saturday's 2-1 win over Blackburn Rovers with a recurrence of an ankle problem, while the latter missed the game entirely with a sore heel.
Fellow defenders Gary Neville and Wes Brown have already been ruled out of the last 16 clash with the Italian champions.