Sir Alex Ferguson will check on the fitness of defenders Rio Ferdinand and Jonny Evans before finalising his Manchester United team to face Wigan at the JJB Stadium tomorrow (Tuesday).
Ferdinand tweaked a calf in training on Saturday that ruled him out of United's derby win over Manchester City, while his replacement Evans limped off with a hamstring injury.
John O'Shea is set to play in central defence if both men are ruled out, with Ferguson set to make other changes; Paul Scholes, Michael Carrick and Wayne Rooney
among those set to return as United hunt the four points required to clinch the title.
Team (from): Van der Sar, Foster, Kuszczak, Rafael, O'Shea, Neville, Ferdinand, Vidic, Evans, Evra, Ronaldo, Nani, Carrick, Scholes, Fletcher, Anderson, Park, Giggs, Rooney, Tevez, Berbatov, Macheda.