It is seven years since United enjoyed the last of their record 11 triumphs in the competition. They have not been victorious at Wembley since their 1999 treble-winning campaign.
Following Saturday's 2-0 win over Arsenal at Old Trafford, United are now just two wins away from rectifying that statistic, which Van der Sar knows they must do to make his weekend heroics worthwhile.
"An FA Cup winners medal would mean a lot despite what I have already won in my career," he said.
"It is there and on my list but I wouldn't look back in regret if I don't win it.
"In any case, it doesn't do a lot for me to lose a semi-final there. Football is about winning trophies. Although we're at Wembley, we are still one match away from the final."
Source: PA