Ferguson saw his side go down 3-2 at home to Tottenham at the weekend and has now named a number of youngsters in their 21-man party.
CFR Cluj beat Braga 2-0 in the first game last Tuesday while United Galatasaray 1-0.
Jonny Evans was available, but missing the game will be Nemanja Vidic, Chris Smalling and Phil Jones who are all suffering with injuries.
Michael Keane and Scott Wootton have been included as cover.
Squad: De Gea, Lindegaard; Buttner, Evans, Evra, Ferdinand, M.Keane, Rafael, Wootton; Anderson, Cleverley, Fletcher, Lingard, Nani, Powell, Tunnicliffe; Hernandez, Kagawa, Rooney, van Persie, Welbeck.
Source: FOOTYMAD
