Rio Ferdinand and Gary Neville are both in contention for Manchester United’s trip to Tottenham.
Ferdinand has yet to play a competitive match for United this season after a thigh injury but is back in training, while Neville proved his fitness in a reserve match last week.
Sir Alex Ferguson may start Antonio Valencia on the bench as the Ecuador winger has had a long journey back from international duty in Bolivia, where he scored in a 3-1 win to give his country a good chance of qualifying for the World Cup.
"Valencia was playing in Bolivia so he'll probably arrive back in November!" said Ferguson. "Just think of a player playing a game in Bolivia on a Thursday morning and expected to be playing at Tottenham on a Saturday, but that's what happens now."
John O’Shea is certain to be missing after suffering a calf injury on duty with the Republic of Ireland, while keeper Edwin van der Sar’s broken thumb will keep him out for another month.
Tottenham Hotspur (from): Cudicini, Assou-Ekotto, King, Hutton, Corluka, Palacios, Crouch, Huddlestone, Kranjcar, Lennon, Defoe, Pavlyuchenko, Keane, Giovani, Naughton, Button, Bentley.
Manchester United (from): Foster, Kuszczak, Neville, Ferdinand, De Laet, Brown, Vidic, Evans, Evra, Fabio, Nani, Carrick, Scholes, Fletcher, Anderson, Giggs, Park, Tosic, Valencia, Owen, Rooney, Berbatov, Macheda.
Key opponent: Aaron Lennon - little right winger is playing superbly and his tussle with Patrice Evra will be intriguing
Prediction: Tottenham 1 United 2 - Goals are likely to be on the agenda but if Ferdinand is back United should end up on top
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