Bosnia striker Edin Dzeko was settling in at City yesterday at a time when new team-mates Micah Richards, Emmanuel Adebayor and Adam Johnson have all expressed concern at limited playing time under manager Roberto Mancini.
At Old Trafford, Ferguson also juggles the same issues. He has not picked the same team in successive Barclays Premier League matches since the end of the 2008-09 season.
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Last night Ferguson was asked on USA radio station Sirius Xm how he kept players happy and said: 'Several things come into it, but first the players have to understand that, at Manchester United, we have to use our squad.
'I'll always explain to a player who I have left out what I am trying to do and the reason for not including him.
'If he has his opinion, great, I am happy to talk it through with him and they always know they may be playing next week and somebody else will have to sit it out.
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'If we win things, it shows the way we have gone about things is correct. If we are winning the Premier League, European Cup or FA Cup, then we've done the right thing.'
Ferguson was also asked for his view on the spate of managerial sackings, which have included his former captain Roy Keane at Ipswich and Liverpool manager Roy Hodgson.
He added: 'The ability is not in question, it is just about the trust that people put in you and managers are just not getting that.'
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Explore more:People: Alex Ferguson, Edin Dzeko, Adam Johnson, Roy Keane, Roy Hodgson, Roberto Mancini, Emmanuel Adebayor Places: Liverpool, Ipswich, Bosnia