Following Paul Scholes' retirement, Ferguson has been on the lookout for a replacement.
Sneijder appeared to fit the bill, particularly as Luka Modric is seemingly bound for Chelsea if Tottenham agree to sell, and Ferguson also suspects Arsenal's Samir Nasri will join Manchester City if he leaves Emirates Stadium.
Speculation has mounted regarding Sneijder over the past few days but, after landing in Seattle following a six-hour flight from Boston, Ferguson rejected the theory outright.
"There is no real interest at this moment in time in Wesley Sneijder," he said.
Ferguson added there was "nothing imminent" in terms of signings, although the underlying theme of his comments suggested there might have been discussion over Sneijder.
"I have not been involved in this situation," he said. "There is no real interest for a lot of reasons. There is nothing I can tell you about it."
Whether there is any likelihood of such a transfer being resurrected is open to debate.
There has been a suspicion Sneijder would welcome a move away from the San Siro and that Inter were prepared to sell their star man if the price was right.
However, the numbers will have to stack up for United given Sneijder is now 27 and his resale value would not be high if he was handed a long-term contract.
Ferguson did admit the search for Scholes' replacement would go on, though, even if getting the right man will prove difficult.
"It is a loss. He was a player of a lifetime. In his 20 years at the club, it is hard to pick out a bad game," said the Scot. "He was such a great, consistent player for us. I don't think we will find another Paul Scholes.
"But hopefully we can replace him. Maybe we will find a different type of player. Manchester United do that.
"Time and time again we have faced this problem. We have lost great players and you are worrying about it.
"But eventually something turns up, either through our youth system or we will identify someone.
"Obviously, there is a bit of work being done on that at the moment by our scouting department.
"But also we are analysing the capabilities of the young players from our youth team. We will give them that opportunity."