The 606 BBC presenter described Gough's pre-match tactics talk before England's Euro 2012 qualifier against Montenegro as 'painfully bad', prompting a war of words.
Savage posted: 'Just in my mates car and he has a radio show on it's painfully bad a cricketer talking football tactics wow I might do the ashes.'
The comment provoked an instant reaction from the irate Yorkshireman and his talkSPORT colleagues who rounded on the Derby County midfielder.
FOLLOW SPORTSMAIL'S TEAM OF WRITERS ON TWITTER War of words: 5Live host Robbie Savage traded insults with talkSPORT presenters
Gough initially replied in a direct post to Savage, saying: 'Hi pal I'm a PFA and PCA member When did you play cricket.'
A wound-up Savage hit back, posting to Gough: 'Mate 28,000 followers well done stick to cricket cos you no f all about football all I no about cricket is you couldn't bat!'
Hitting back: Ex-England cricketer Darren Gough
Stan Collymore then waded into the heated debate riling the ex-Wales international, tweeting: '5 live offered me the 606 gig for this season,and I turned it down,because 606 has virtually a captive audience,and I get much more pleasure from what I've achieved with Call Collymore than I ever could from 606. If you've got it, you do your own, not piggyback on others.'
Savage responded: 'Yeah right I'm enjoying doing your Mirror column as well Stanley.'
TalkSPORT host Andy Goldstein was the next to enter the argument later in the evening, saying: 'Why is @RobbieSavage8 having a pop at talkSPORT? It's like me playing for Derby and slaughtering Barcelona.'
Savage told the former Soccer AM presenter: 'Can't be bothered with nuggets like you who nobody knows pal 600 games later I'm still there! I'll tune in at 3am to you.'
Hundreds of followers on the social networking site posted their support for the respective sides with Barnsley boss Mark Robins and Sky Sports cricket pundit David Lloyd also casting their opinions.
Ex-Manchester United striker Robins wrote to Savage: 'Darren Gough is a good man and a great bowler but he's not a football pundit end of.'
Taking the mic: It is not first the first time Collymore has been involved in trading insults between the two rivals stations
The incident is the latest in a long line of insults between the rival radio broadcasters.
Earlier in the summer Collymore was furious with highly provocative commentator Alan Green after he repeatedly mentioned on air during the World Cup in South Africa that BBC listeners should 'beware cheap imitations'.
Green later apologised for his comments but the raging hostility between the two warring stations clearly looms large after this latest public row.
Sportsmail on Twitter: Follow regular updates from our team of writersTime to switch off! Match of the Day is just 'stale and smug', blasts CollymoreCharles Sale: Stan Collymore slams BBC Radio 5 Live pundit Alan Green over 'cheap' shotTalkSPORT pulls off major coup by snatching commentary rights from BBC
Explore more:People: David Lloyd, Darren Gough, Robbie Savage, Stan Collymore Places: Barcelona, Montenegro, United Kingdom, Wales, South Africa