The prestigious award is usually given to an attacking player and only two defenders - John Terry (2004-05), Paul McGrath (1992-93) - have won the award in the Premier League era.
But Ferdinand told ManUtd.com: "I think Vida will be in the running for Player of the Year. He's probably been our most consistent player along with Ryan (Giggs) and Edwin (van der Sar).
Red Devils: Rio Ferdinand hitches a ride on defensive partner Nemanja Vidic after United score against Inter Milan
2008 winner: Cristiano Ronaldo
'Those three are probably our stand-out players of the season in terms of consistency.
'The attackers normally get the accolades and the adulation so it would be nice to see a defender win it.
'JT [John Terry] won it a few years ago, but over the years not many centre halves have won it. So it would be good to have a defender win.'
Vidic has continued the outstanding form that took United to domestic and European glory last season, establishing a solid partnership with Ferdinand at the heart of defence.
The 27-year-old has also chipped with seven goals in United's 2008-09 campaign although, with six bookings and three red cards in all competitions, his disciplinary record could improve.
PFA PLAYER OF THE YEAR WINNERS2009 - TBC
2008- Cristiano Ronaldo, Man Utd
2007- Cristiano Ronaldo, Man Utd
2006- Steven Gerrard,Liverpool
2005- John Terry, Chelsea
2004- Thierry Henry, Arsenal
2003- Thierry Henry, Arsenal
2002 - Ruud Van Nistelrooy, Man Utd
2001- Teddy Sheringham, Man Utd
2000 -Roy Keane, Man Utd
1999- David Ginola, Tottenham Hotspur
1998- Dennis Bergkamp, Arsenal
1997- Alan Shearer, NewcastleUnited
1996- Les Ferdinand, Newcastle United
1995- Alan Shearer, Blackburn Rovers
1994- Eric Cantona, Man Utd
1993 - Paul McGrath, Aston Villa
1992- Gary Pallister, Man Utd
1991 - Mark Hughes, Man Utd
1990- David Platt, Aston Villa
1989- Mark Hughes, Man Utd
1988- John Barnes, Liverpool
1987- Clive Allen, Tottenham Hotspur
1986 - Gary Lineker, Everton
1985- Peter Reid, Everton
1984 - Ian Rush, Liverpool
1983- Kenny Dalglish, Liverpool
1982- Kevin Keegan, Southampton
1981 - John Wark, Ipswich Town
1980- Terry McDermott, Liverpool
1979 - Liam Brady, Arsenal
1978- Peter Shilton, NottinghamForest
1977- Andy Gray, Aston Villa
1976- Pat Jennings, Tottenham
1975- Colin Todd, DerbyCounty
1974- Norman Hunter, Leeds United
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