The decision was taken when he was re-assessed this morning by the Northern Ireland medical staff after missing training last night.
Chelsea v Liverpool: History old and new gives Rafa Benitez hope over expectationWhy Northern Ireland, Wales and Scotland will be the big victims of FIFA quotasSir Alex Ferguson set to give United youngsters a chance in Carling CupNigel Worthingtons Northern Ireland make amends with solid displayHowever, there was no improvement overnight and Evans will continue treatment at his club.
Manager Nigel Worthington has called up Evans' brother Corry, who is also a Manchester United player.
The 19 year-old is currently in San Marino with the Under-21 squad for a Uefa championship qualifier tonight and will join up with the senior squad on Wednesday.
Worthington is short of defenders as Aaron Hughes and Chris Baird have been rested, Gareth McAuley is injured and Shane Duffy has opted to play for the Republic of Ireland.