As Neville waits to learn whether the one appearance he needs to reach 600 for the Old Trafford outfit will come in the Champions League clash with Rangers tonight, the question of how long his long-time team-mates can go on for has cropped up again.
Sir Alex Ferguson admitted United would almost certainly need to "stretch" themselves in the transfer market when the time comes for Giggs and company to call it a day.
Ferguson has not given up hope of getting another two years from those ageing legs, although given his own injury problems, Neville's career seems likely to come to a close first.
Towards the end of last season, Neville felt he was three games away from retirement, only for Ferguson to hand the full-back a new contract.
That same decision had already been made for Giggs and Scholes.
And after starting the current campaign in impressive fashion, Neville feels the pair still have plenty of service to give.
"I don't see why Ryan and Paul cannot continue what they are doing given how well they are playing at present," he said.
"Ryan is 37 in November and I can't see any difference. It is incredible really.
"I certainly don't see any players better than them.
"They manage themselves brilliantly, on and off the pitch.
"The manager is looking at 25 to 30 games a season off them now, not 55 so they could play on for another few years."