Both men would have missed Sunday's trip to Chelsea had it not been postponed but have now returned to training, along with Michael Carrick and Nani, who have also been affected.
Fever pitch: Defender Vidic (left) is expected to be fit to to face Sunderland
Paul Scholes (groin) and John O'Shea (calf) are both out as United look to extend their lead at the top of the table.
Team (from): Van der Sar, Kuszczak, Rafael, Brown, Ferdinand, Vidic, Smalling, Evans, Evra, Fabio, Nani, Obertan, Carrick, Fletcher, Gibson, Anderson, Park, Giggs, Bebe, Rooney, Berbatov, Macheda, Hernandez, Owen.
CLICK HERE FOR THE REST OF THE BOXING DAY PREMIER LEAGUE TEAM NEWS Explore more:People: Paul Scholes, Alex Ferguson, Bebe, Nemanja Vidic, John O'Shea, Nani, Michael Carrick