The youngster received his marching orders for two bookable offences at White Hart Lane.
Dismissed: Rafael (left) was controversially sent off at Tottenham
Brother Fabio, plus more experienced duo Wes Brown and John O'Shea, are all in contention to fill the vacancy, with Ferguson also expected to make a couple of extra changes as his side look to retain top spot.
Team (from): Van der Sar, Kuszczak, Lindegaard, O'Shea, Brown, Neville, Ferdinand, Vidic, Smalling, Evans, Evra, Fabio, Nani, Obertan, Carrick, Fletcher, Scholes, Gibson, Anderson, Giggs, Bebe, Rooney, Berbatov, Hernandez, Owen.
CLICK HERE FOR THE WEEKEND TEAM NEWS IN THE BARCLAYS PREMIER LEAGUE Explore more:People: Alex Ferguson, Bebe, Wes Brown, John O'Shea, Nani Places: Birmingham