But despite City's trophy drought, United defender Evra insists that the mentality between the two clubs is wholly different, with United putting silverware ahead of local bragging rights.
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'Maybe that's the difference between Manchester United and Manchester City. We play the game to win and to win the Carling Cup, they play to win against Manchester United.
'For us, it is not just about beating Manchester City. Yes, it is an important game, but Manchester United play a lot of big games.'
Evra admits that United's dramatic 4-3 victory over City at Old Trafford in September was the most incredible fixture he has played at Old Trafford.
That defeat sparked the run of poor form that ultimately cost manager Mark Hughes his job at Eastlands and Evra believes that another United win could lead to more problems at City.
He said: 'When we beat City 4-3 it was crazy. Everyone was on the pitch at the end and the noise was incredible.
'More importantly, City had been doing well, but when they lost that game against us, they started to struggle.
'If we win this match it might affect them again. Every time it is the same.
'Now people say Mancini is a great manager because he won the first four games, but if he loses against United, they will say he is the worst. That is the way football is now.
'Every year I have been at Manchester United I have won two or three trophies. For me now, it is normal.
'If we don't win the league it will look like I have not done my job properly. I only have the mentality to win, every year.'