The Black Cats saw off Peterborough United as a Daniel Blanchett own goal and a penalty from summer signing Fraizer Campbell sealed success.
Wolverhampton Wanderers put four goals past Scunthorpe United in a 4-2 triumph with Greg Halford among the goals as he bagged a brace.
Blackpool overcame Everton 2-1 with goals from David Vaughan and Jason Euell proving too much for the Toffees, who netted via striker Jo.
Premier League side Birmingham City took a one-goal advantage through James McFadden against Crewe Alexandra but ultimately fell to a disappointing 4-1 defeat.
Bolton Wanderers were held to a 1-1 draw against Hearts after Christian Nade cancelled out Fabrice Muamba's opener, while Millwall saw off Welling United3-2.
Oxford United overcame Aston Villa 2-0 as Alfie Potter struck twice, a seven-goal thriller saw Doncaster beat Brigg Town 4-3 while Marlow overcame Wycombe 1-0.
Stockport County fell to a 3-1 loss versus Real Valladolid despite taking the lead through Gianluca Havern, while a Manchester United XI beat Altrincham 2-0.