United are in the enviable position of being three points clear in the Premier League title race and through to the semi-finals of the UEFA Champions League, heading into the closing weeks of the season.
With the possibility of a game every three days for the remainder of the campaign, the Scot has already turned to his young stars for the FA Cup semi-final against Everton last weekend - a game that ultimately ended in defeat.
However, facing a tougher run in and a potential three more games than their nearest league challengers Liverpool, the United boss remains convinced that having fresh legs to call on will be the key to success.
"You have to be up for every game or you can get punished, so I will juggle the squad in the hope that we can progress in both the Premier League and Champions League," he said.
"We have a quality squad which is rich in terms of both ability and numbers, and I intend to make full use of it."
'Non-stop football'Of course, United are no strangers to the pressure of chasing multiple silverware, having famously secured the Premier League, FA Cup and Champions League in 1999.
The league went down to the final day on that occasion, and whilst United will hope to have the title wrapped up before then, Ferguson is relishing seeing his side being pushed to its limits as they were in their Treble-winning year.
"This is the time I love the best. Non-stop football, with every match now of immense significance, and the challenge of competing on a couple of fronts," he added.
"But I will be deploying the full range of our resources as I seek to give the players the energy you need at this level. It's what I did when we won the Treble, resting players and bringing others in as I tried to pick teams fizzing for the fray.
"Life at the top of the English game is fierce and relentless. The pace and intensity takes a toll, especially with so many fixtures coming so quickly on the last lap for trophies."