Clubs such as Liverpool and Chelsea have struggled to keep all of their players happy in the past with the promise of regular football or the guarantee of playing in big games.
Ferguson, however, appears to have found the balance, with very few stories of fall-outs or discontent leaking from the camp.
Those players that missed the chance to play against Inter Milan in the UEFA Champions League will likely figure in Sunday's Carling Cup final against Tottenham.
Winning mentalityAsked his secret at juggling such a huge squad, Ferguson said: "There is a winning mentality at the club which helps.
"We have been successful. Everyone wants to share in that and be involved in a winning team.
"That is one strong point and it is an important one. Also, this is a good club and a well-run club."
The likes of Nani and Anderson are good examples of United's ability to utilise their strong squad.
Since their arrival in the summer of 2007, both players have been content in playing in a rotating squad.
BalanceNeither figured in last year's Champions League final which may be the case should United reach Rome on 27th May.
"I don't suppose it's easy for them but they have come to a club where we operate a squad and they recognise that," said Ferguson.
"It is not as if they are not playing. Anderson has played in a good proportion of matches, including some important ones.
"He is regarded very highly here and Nani would come into the same category."