The reigning champions returned to the Premier League summit after a 1-0 win over the Hammers, with Scholes supplying the pass for Giggs' winning goal on 62 minutes.
Scholes spread the play to his long-serving team-mate, who jinked past two players before curling a right-footed shot beyond Robert Green.
United boss Ferguson admits Upton Park has been a tough venue in the past and that prompted his decision to start with Giggs and Scholes.
Fantastic atmosphere"We felt today, knowing that West Ham is always a difficult ground for us, that we should have the most experience we can," Ferguson told Sky Sports 1.
"Ryan and Paul Scholes have been here so many times and they know exactly what is needed here.
"Michael Carrick, Carlos Tevez and Rio Ferdinand are former players here and that also helps actually to handle the atmosphere.
"It was a fantastic atmosphere and they really get behind their team, and we've beaten a very good team today."
Edwin van der Sar set a new British league record after a 13th consecutive clean sheet and Ferguson praised the United keeper and his defence.
FocusHe added: "The clean sheets have been a topic, but it doesn't just change the emphasis on our game.
"I think today we've had some fantastic possession of the ball and the players we've got on the pitch are attackers - Cristiano, Dimitar, Carlos, Ryan and Paul Scholes, and Michael Carrick.
"What the back four have done is really focus and concentrate on their job. They've got pace and are quick and, of course, to have a goalkeeper like Edwin van der Sar is just fantastic."