Officers were called to the England frontman's mansion in the village of Prestbury, Cheshire, at 8.30pm after a mob of up to 30 people descended on the property.
The apparent fans' protest comes after Rooney, 24, dropped the bombshell that he no longer wanted to play for the Red Devils.
And there is rising speculation that the former Everton player may leave to join United's great rivals, Manchester City - a nightmare scenario for fans of the Old Trafford outfit.
The striker's refusal to sign a new contract was revealed by a crestfallen Sir Alex Ferguson earlier this week and has been met with rising anger by supporters of the club.
Rooney's home, Candysfield, which he shares with his wife Coleen and son Kai, is down a normally quiet tree-lined drive and surrounded by a wall and gates for added security.
The house is on a 'millionaires' row' with Rooney's neighbours including fellow United players Wes Brown and Michael Carrick.
Cheshire Police confirmed on Thursday night that an incident had occurred in Prestbury, an affluent village south-east of Manchester, but refused to give further details.
A spokesman for the force said: "Cheshire Police can confirm that at 8.30pm, a call was received from a resident in Prestbury regarding 20 to 30 people assembling outside their address.
"Police attended the scene and the group dispersed peacefully. No offences were disclosed."