Manchester United take on Everton while Arsenal or Hull City face Chelsea in the semi-finals of the FA Cup.
Everton were 2-1 victors against Middlesbrough this weekend and now tackle the Red Devils, who are seeking an unprecedented quintuple.
The tie will be a repeat of the 1995 final in which the Toffees recorded a shock 1-0 win thanks to a Paul Rideout goal.
However, they have beaten United just once since that game 14 years ago.
Arsenal overcame Burnley in the fifth round of the competition on Sunday and tackle Hull in the quarter-finals, with Chelsea awaiting the winners in the last four.
A clash for the Blues with London rivals Arsenal would be a repeat of the 2002 final, which the Gunners won 2-0.
Arsenal must first dispose of Hull at Emirates Stadium in a game which will be played on 17th or 18th March.
The semi-finals will be played on 18th and 19th April at Wembley.
FA Cup semi-final draw:
Arsenal/Hull City v Chelsea
Manchester United v Everton