Arsenal face a stiff task in the last 16 of the Champions League after they were drawn against Spanish champions Barcelona.
Barcelona eliminated Arsenal in the quarter-finals last season thanks to a virtuoso display by Lionel Messi and are the bookmakers' favourites again following last month's 5-0 thrashing of Real Madrid.
Tottenham, top scorers in the group stage, also face a stiff test, against AC Milan, in their first experience of the knockout stages of the Champions League.
Milan are currently six points clear at the top of Serie A and with plenty of Champions League experience in their ranks.
Chelsea were given arguably the easiest draw of the round, up against Danish champions FC Copenhagen, while Manchester United will play Marseille.
The other ties see Lyon take on Jose Mourinho's Real Madrid, holders Inter, now managed by Rafa Benitez, will face Bayern Munich, Valencia will play Schalke and Roma have to overcome Shakhtar Donetsk.As it happened:
11.25am - FULL CHAMPIONS LEAGUE DRAW:
Roma v Shakhtar
AC MILAN V TOTTENHAM
Valencia v Schalke
Inter Milan v Bayern Munich
Lyon v Real Madrid
ARSENAL V BARCELONA
MARSEILLE V MANCHESTER UNITED
COPENHAGEN V CHELSEA.
11.21am - COPENHAGEN V CHELSEA
11.20am - MARSEILLE v MANCHESTER UNITED
11.18am - Lyon v Real Madrid, ARSENAL v BARCELONA
11.17am - Valencia v Shalke, Inter Milan v Bayern Munich
11.16am - First two ties - Roma v Shaktar Donetsk, AC MILAN V TOTTENHAM HOTSPUR
11.15am - The main rules of the draw are that no teams from the same country can draw each other and teams that played each other in the group stage cannot be drawn against one another. Rememeber that.
11.10am - Here's who can draw who:
CHELSEA: Inter Milan, AC Milan, Roma, Lyon, FC Copenhagen, Valencia.
TOTTENHAM: AC Milan, Roma, Lyon, FC Copenhagen, Valencia, Marseille.
MANCHESTER UNITED: AC Milan, Roma, Inter Milan, Lyon, FC Copenhagen, Marseille
ARSENAL: Barcelona, Real Madrid, Bayern Munich, Schalke.
11.00am - Tottenham, Inter Milan, Schalke, Lyon, Manchester United, Valencia, Barcelona, FC Copenhagen, Bayern Munich, Roma, Chelsea, Marseille, Real Madrid, AC Milan, Shakhtar Donetsk, Arsenal. Things should be kicking off any minute now.
10.55am - For the fourth time in five seasons all of England's four Champions League representatives have made it through to the last 16. Follow the draw live on Football.co.uk as we find out the fate of Chelsea, Manchester United, Arsenal and Tottenham.