Having almost come a cropper in Denmark once earlier in the competition, when it required a last-minute own-goal to stave off elimination to Midtjylland, City manager Mark Hughes will be eager to ensure there are no slip ups.
But Hughes' opposite number, former Wimbledon player Stale Solbakken, is not impressed by the Eastlands revolution.
"The amounts of money that have been mentioned are incredible," Solbakken said. "I think that such incredible sums will take part in destroying football.
"They are creating too big a mental distance between what we call reality and then Manchester City."
Although he did not mention the failed attempt to sign Brazilian superstar Kaka, Solbakken could have been referring to it with a stinging attack on how much difference the money being invested in City will actually make.
"The hardest part for City is that they, by tradition, are not a big football club and therefore all the money in the world does not make a difference for them," he added.
"They brought in Wayne Bridge even though he is only marginally better than what they had already and that says how hard it is to get the best players even though you have lots of money."