Club officials have slashed prices for the game which is due to be played on 16th April at the City of Manchester Stadium.
Adults can buy tickets for the match for just £5, while children can get into the ground for £1 leading many to believe a bumper crowd will turn up.
Hughes knows Martin Jol's side will provide stern opposition and that his team will need all the support from the club's faithful if they are to progress to the semi-finals.
Fantastic response"There's been a fantastic response to the club's initiative to cut the prices," he told Sky Sports News. "It's just a thank you from the club.
"We're very mindful of the current economic climate. I think everybody has had to try and cut their cloth accordingly.
"So we were trying to make a gesture in that respect, but we're hoping for a big crowd as well because we're up against a quality side and if we get in the situation where we need that extra five or ten per cent then that could very well come from the crowd.
"So if we've got a huge vociferous crowd in the second leg that could be the difference between winning the tie or going out of the competition. So they'll very much become the 12th man for us."