Leeds were rewarded for their victory over Tottenham with a trip to the Barclays Premier League champions.
Neil Warnock's men knocked out Spurs 2-1 at Elland Road to book a trip to the Etihad Stadium in the pick of the ties.
Non-league Luton, who claimed a famous 1-0 win at Norwich on Saturday, missed out on a plum draw with a top Premier League side as they got Millwall at home.
Bringing back memories of the trouble years ago ... "I Predict A Riot".
FA Cup fifth round draw:
Huddersfield or Leicester v WiganMK Dons v BarnsleyOldham v EvertonLuton Town v MillwallArsenal v BlackburnManchester City v LeedsManchester United v ReadingMiddlesbrough v Brentford or Chelsea
Ties will be played on the weekend of February 16/17.
Source: Manchester City MAD