The 20-year-old made his debut ahead of schedule as a substitute in the weekend's 4-0 defeat at Tottenham after injury to Daniel Agger.
Coates is now set for his first start in the Carling Cup tie at Brighton less than a month after arriving from Nacional in his homeland for a fee believed to be in the region of ?7million.
Bad start: Sebastian Coates (right) and Liverpool crashed to Spurs on Sunday
But the 6ft 6in centre-back, named young player of the tournament in his country's Copa America triumph this summer, is relishing the test of moving to, and playing in, a different country.
'The biggest attraction was the challenge: to come to an unfamiliar place - a huge club - and make a name for myself,' he told LFC magazine.
'So far in my career, I have been very lucky; to play for Nacional, to play in the Copa Libertadores, to win the Copa America.
'There has been a lot of success in a short period of time but I have achieved that in a place where I am most comfortable.
'Now, I am here, in a different country, in a different league, with different team-mates.
'The best players are successful wherever they go. I am determined to become an important player here at a historical stage of the club's future.'
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