Liverpool led through Ryan Babel's thunderbolt only for Lisandro Lopez to pop up with a last-gasp equaliser, meaning Rafael Benitez's side must now win their two remaining games in Group E and hope already-qualified Lyon can do them a favour against Fiorentina if they are to reach the last 16.
"If anyone can do this, Liverpool can. But now it (qualification) is not in our own hands, it does not only depend on what we do," said Reina.
"We must continue to show heart, passion and belief.
"We were unlucky, but we must keep fighting until we have more options with players getting fit again.
"I felt we had done enough to have won, and deserved it too. Maybe not beforehand in the previous matches when we did not play well.
"But this was different, this was a much better performance. When we play like we did in Lyon, we know we are good enough.
"Now it is very, very difficult for us. But we must show strong character and fight right to the end. We know we have enough good players to sort this out.
"The players will take heart from this, at least we know we are getting back to the form we know we should be producing every week."