Liverpool will be without midfield duo Javier Mascherano and Yossi Benayoun for Tuesday's Champions League clash with Fiorentina.
Mascherano is suffering from sickness despite featuring in Saturday's 6-1 rout of Hull City in the Premier League.
Benayoun picked up a leg injury during the same game and neither player has travelled to Italy.
Meanwhile, the Reds has revealed that defender Daniel Agger will step up his comeback from a back problem which has sidelined him since pre-season during a reserve-team game against Manchester City on Tuesday.
"It is fantastic to see Daniel back and it's a great boost for everyone at the club," reserve team manager John McMahon told the club's official website.
"It's always great to see quality players come back from injury and this will be a perfect game for him to make his comeback.
"It's a fantastic stadium with a great pitch and it is always a fantastic boost for the young lads when they have a top professional like Daniel playing alongside them.
"The young lads look up to him and they can learn from him as well."