Rafa Benitez has not given up hope of his Liverpool side defying the odds and reaching the semi-finals of the Champions League.
The Reds slumped to a 3-1 defeat against Chelsea at Anfield in the first leg of their last-eight encounter last week, but Benitez is keen to revive the spirit of Istanbul in the build-up to the game.
Four years ago in Turkey, Benitez's side produced one of the greatest comebacks in the history of the game when they beat AC Milan on penalties in the Champions League Final after trailing by three goals at half-time.
Benitez said: "In this moment we have nothing to lose, so Chelsea are under pressure. They have to win. But they have experience in the Champions League and quality.
"For both teams the first goal will be important but for us it could clearly make a massive difference. It's football. In football anything can happen. We have to believe and we have to think we can do it.
"Every single press conference you ask me about Istanbul but it's right. We have some players who were there, they know how to do it. Hopefully the other players will learn to do it too and we can have another fantastic night for the club.
"We know we can do it. We can score goals away against top sides - we also have the experience of winning 4-1 at Old Trafford.
"If we can push and play well and start well, our fans will be even more behind us. They'll be behind the team because of the game and because everyone knows if we achieve something now it will be linked to the (Hillsborough) memorial.
"Clearly we know it's an important week for the fans and the club. We have some players who know a lot of people - they've been here for a long time. That could be an inspiration for a lot of them."