Liverpool's Premier League clash against Tottenham Hotspur on Sunday has been postponed.
Three of Saturday's top-flight encounters - Fulham against Portsmouth, Burnley versus Stoke City and Sunderland's match at home to Bolton - were called off earlier on Friday.
A Liverpool spokesman said: "Although the Anfield pitch is perfectly playable for the game, the problem we face is the icy condition of the approach roads and paths in the immediate vicinity of the stadium.
"The safety of our fans is paramount and an assessment of both the prevailing conditions and the weather forecast for the next 48 hours has been made in arriving at the decision to call off the match. Both local police and the City Council were fully involved in this assessment."
Only four of Saturday's Premier League games have beaten the extreme weather conditions although the forecast remains dire for this weekend.