Charlie Daniels is poised to return to the Leyton Orient starting line-up for the trip to Southampton.
The defender suffered a knee injury in pre-season but has recovered quicker than expected and proved his fitness in a behind-closed-doors friendly against Reading this week.
Sunderland youngster Michael Liddle was drafted in for a month as cover for Daniels but he has missed the last two matches with a groin injury so Daniels should start
Midfielders Matthew Spring and Stephen Dawson and striker Alex Revell missed training earlier in the week with knocks and will be checked over.
Rookie striker Jake Argent, who signed his first professional contract this summer, is the only definite absentee with a long-term knee ligament problem.