Leeds will be without suspended winger Robert Snodgrass for the home clash with Preston.
Snodgrass, who recently returned from a knee injury and made only his second appearance of the season in Saturday's win over Sheffield United, is serving a one-game ban after being sent off for a second bookable offence.
He replaced Lloyd Sam at the weekend, so the latter can expect to start again, although manager Simon Grayson has plenty of options in all areas.
Grayson must decide whether to stick with Bradley Johnson, preferred in central midfield to Neil Kilkenny, while Sanchez Watt and Amdy Faye, yet to make his first appearance for the club, were unused substitutes on Saturday.
Luciano Becchio partnered Davide Somma up front against the Blades, but Ross McCormack and Ramon Nunez could also come into contention.