But the South American proved a handful alongside Beckford at Manchester United in the previous round and is likely to return.
Central defender Patrick Kisnorbo could also be back in contention after missing out in midweek - Leigh Bromby stepped up to partner Richard Naylor in central defence - while goalkeeper Shane Higgs is still dogged by a thigh problem, so Casper Ankergren will continue.
It will be the first meeting between the two sides in over six years. Tottenham beat Leeds at Elland Road 1-0 in a Premier League game in January 2004 after winning at White Hart Lane 2-1 the previous August.
The match kicks off at 5.15pm.