Italy coach Roberto Donadoni has revealed he will make at least three changes to his side for Friday's must-win Group C meeting with Romania.
The reigning world champions need three points against Romania in Zurich to keep alive their hopes of qualification for the knock-out stages after they slipped to an opening 3-0 defeat at the hands of Netherlands.
"I will make three or four changes," confirmed Donadoni.
"Among those changes, (forward) Alessandro Del Piero and (defender) Giorgio Chiellini will be included."
AS Roma midfielders Simone Perrotta and Daniele De Rossi are also set to be included after being omitted from the Netherlands defeat, while defensive duo Christian Panucci and Marco Materazzi have been passed fit despite suffering minor knocks.
"We have two games still to play and we aim to make amends for our defeat against Holland," added Donadoni.