Ipswich manager Roy Keane will hand a debut to goalkeeper Marton Fulop for the tough trip to face Middlesbrough.
Fulop signed a two-year deal on Thursday after completing his move from Sunderland and will go straight into the starting XI at the Riverside.
Fellow new signing Mark Kennedy is poised to make his debut at left-back while Keane is considering handing a first start to midfielder Luke Hyam after the teenager impressed during pre-season.
Town`s most high-profile teenager Connor Wickham will not feature however as the striker is recuperating after injuring his ankle in training.
Defender Damien Delaney is another casualty for Keane. The Irishman was forced to endure two operations to remove a blood clot from his leg and is set for an extended lay-off.