Strikers David Healy and Daryl Murphy are both hoping to make their debuts for Ipswich when Middlesbrough visit Portman Road.
Manager Roy Keane raided former club Sunderland to sign the the pair on loan on transfer deadline day and they could both start against Gordon Strachan's side.
Defender Alex Bruce was surprisingly allowed to join Leicester on loan on Monday so will not be involved while striker Tamas Priskin moved to QPR.
Captain Jon Walters continues to be ruled out by a hamstring injury and is joined on the sidelines by goalkeepers Richard Wright and Brian Murphy.
Wright has stepped up his comeback from a knee injury and could be available by March while Murphy could be available to make his debut in the next few weeks after injuring his ankle.
Winger Luciano Civelli will not be available until next season as his troubled recovery from a serious knee injury continues.