Priskin joined Town on Friday and is set to start as striker Pablo Counago - who turned down a move to Swansea this summer - picked up a groin injury on the first day of pre-season and remains sidelined.
Left-back Ben Thatcher has returned to training this week for the first time since picking up a medial ligament injury against Norwich in April but will not feature, while Keane is hopeful David Wright will be fit.
Wright has been struggling with a rib injury but is expected to travel to leave Argentinian winger Luciano Civelli as the only other absentee as he continues his long rehabilitation from a serious knee injury.
New signings Damien Delaney, Lee Martin and Jack Colback could all make their debuts but fellow new signing Colin Healy will serve a one-match suspension carried over from former club Cork City.
The match kicks off at 12.45pm.