Playmaker Wesley Sneijder was amongst the absentees as Inter Milan named their squad for Tuesday's Champions League clash with CSKA in Moscow.
Brazil full-back Maicon and Serbia captain and midfielder Dejan Stankovic will also miss the crunch encounter.
Having lost their opening match at home to group outsiders Trabzonspor, Inter are desperate to take something from the game.
Nigerian midfielder Joel Obi will make the trip but such are Inter's injury problems that coach Claudio Ranieri has called up youth team midfielders Lorenzo Crisetig and Andrea Romano into his 21-man squad.
He also has to do without forward Diego Forlan, who is cup-tied having represented Atletico Madrid in the Europa League qualifying rounds.