Hull followed up Tuesday's draw with Premier League leaders Chelsea by defeating Manchester City 2-1 at the KC Stadium to climb out of the relegation zone.
Phil Brown's side had not won since November but were buoyed by their performance against the Blues and deservedly took a 31st-minute lead through the impressive Jozy Altidore.
The visitors then found themselves two down nine minutes after the break thanks to a rocket from George Boateng.
And although Emmanuel Adebayor quickly pulled one back, they rarely threatened to equalise.
The talking point before the game was the inclusion of Wayne Bridge after two months out with a knee injury and amid the fall-out from John Terry's alleged affair with his former partner.