The draw maintains Hull's unbeaten start in their pre-season fixtures so far this summer.
Caleb Folan missed a good opening for Hull on 26 minutes when unmarked inside the box he headed Craig Fagan's cross wide.
The best chance of the half fell to Wednesday when Leon Clarke ran clear onto Marcus Tudgay's flick-on, but Hull keeper Matt Duke kept out the striker.
Both sides had chances to win it late on when Kamil Zayatte cleared Akpo Sodje's deflected shot from under his own crossbar.
Hull substitute Will Atkinson saw his effort kicked off the line in the closing stages as both sides had to settle for a draw.