Rosenior was stretchered off in the midweek draw with Leeds following an aerial collision with Lloyd Sam.
The right-back sustained head and neck injuries in the collision and, although he has been given the all-clear by doctors, he may not be ready for Saturday.
Harper was replaced by Nick Barmby in the second half against Leeds due to the recurrence of a foot injury he initially sustained during pre-season and is also doubtful.
Defender Nolberto Solano could return following a thigh strain, but manager Nigel Pearson will still be without striker Caleb Folan (knee), goalkeeper Vito Mannone (groin) and winger Richard Garcia (knee).
Recent signing Tijani Belaid is pushing for a place in Pearson's starting line-up after making his debut as a second-half substitute on Tuesday night.