Among those to make the cut is Aussie goalkeeper Schwarzer, who the Cottagers managed to keep out of the clutches of Arsenal on transfer deadline day.
Bobby Zamora is also included, with much expected of the England international again this term.
New signings Rafik Halliche, Carlos Salcido and Moussa Dembele have been handed squad numbers by Hughes, as have key duo Zoltan Gera and Clint Dempsey.
Andrew Johnson has been called upon and will be hoping to leave his injury nightmare in the past and kick-on in 2010/11.
Diomansy Kamara is also chosen within the attacking ranks, despite having been loaned out to Celtic towards the end of last season.
Premier League clubs had until 5pm on Wednesday to compile their squad lists, with new rules stipulating that each side had to select at least eight 'home-grown' players.
Squad: Mark Schwarzer, David Stockdale, John Pantsil, Fredrik Stoor, Aaron Hughes, Rafik Halliche, Chris Baird, Brede Hangeland, Carlos Salcido, Stephen Kelly, Zoltan Gera, Clinton Dempsey, Bjorn Helge Riise, Dickson Etuhu, Kagisho Dikgacoi, Danny Murphy, Jonathan Greening, Simon Davies, Damien Duff, Andrew Johnson, Diomansy Kamara, Moussa Dembele, Bobby Zamora, David Elm, Eddie Johnson.