Mousa Dembele pounced in injury time to give Fulham a 2-1 victory in a bruising contest that saw England striker Bobby Zamora stretchered off with a broken ankle.
The impressive Dembele, a £5million summer arrival from AZ Alkmaar, struck his first Barclays Premier League goal with a fine equaliser in the 49th minute.
And he also delivered the match-winning free-kick in the dying moments after Wolves' Christophe Berra had been sent off for picking up two yellow cards.
Jelle van Damme gave Wolves an early lead when he tucked home Kevin Doyle's cross, the first act of a traumatising first half for Fulham capped by the departure of Zamora.
Zamora was brought down by a hard challenge from Karl Henry and although the Wolves skipper won the ball, his victim's right ankle was trapped in the tackle and his leg buckled awkwardly.
The 29-year-old, who won his first England cap last month with more seemingly imminent, thumped the turf in agony and was given oxygen before being carried off the pitch three minutes later.