Fate determined that Rooney's first Manchester United game since allegations about his sex life is at his first club, Everton.
'It should be amusing,' said Jagielka. 'Up on Merseyside he normally gets a little bit of stick. I'll be giving him a little bit as well if he plays. We've spoken about it.
Turning up the heat: Everton's Phil Jagielka has vowed to make life as difficult as possible for Manchester United star Wayne Rooney
'All the boys know who's playing who. It's always interesting playing against people who you've just been away with in the week.'
Goodison fans have had it in for Rooney since his defection to United six years ago and the Everton and England defender admits it will probably happen again, fuelled by the allegations.
'He normally gets a bit of stick anyway. I can't see that changing on Saturday,' said Jagielka. 'I'm sure Wayne can deal with it. He's a tough lad and he'll let his football do the talking.'
Rooney scored England's first goal in a 3-1 win in Switzerland on Tuesday, his first from open play since injuring an ankle on Champions League duty in March.
Memories are made of this: Rooney celebrates scoring a crucial goal for United at Goodison Park in 2007
Jagielka said: 'He's done what he's put in the team for and he created some good chances as well, but he was there, the right man at the right time to slot in the opener.'
'I don't really have an in-depth view of how he's been feeling. I'm not exactly best of friends with Wayne but he seems his normal self.'
Jagielka's own form has been impressive for England, giving manager Fabio Capello a selection problem when Rio Ferdinand and John Terry are back from injury.
'If they're fit, they're fit,' said Jagielka. 'The manager chooses the players he wants to play. We've won two games, done pretty well as a team and I've been part of that team.
'There's nothing much else I can do - except maybe score a couple of goals.'
Rooney hailed for forgetting trouble and strife to steer England to victoryA true pro! Swiss roll for Fabio Capello as Wayne Rooney thinks of England at lastEVERTON FC