The Blues boss knows his players need to improve their quality in the final third of the pitch if they are to recover from Saturday's derby defeat by beating Chelsea.
And he wants Saha, who has only scored once in his last eight appearances despite notching 13 overall this season, to lead the way.
He said: 'If we can get our centre-forwards right I think we can cause Chelsea problems.
'I'm looking for Louis to contribute more goals. A lot of his goals have come in the early part of the season.
'He has great talent and ability. He does thrive on a lot of confidence and needs that confidence and self belief.
'We've shown a lot of confidence in him in keeping him here and we want him to get the goals to go with it.
'He has played well in some games lately, but he hasn't got the goals and we want him to get that goal-scoring form back.'
Moyes insists Saha, who was tracked by Spurs and Arsenal before signing a new deal last Friday, has the qualities that can command big transfer fees in other players.
He said: 'Louis is a player who has that level of quality that people are looking for.
'But I would argue that in the last few games we have missed quality in the final third that only money can purchase.